Resuming from hibernate is not working properly. There is a bug open for this issue, which contains a workaround.
echo 'add_dracutmodules+=" resume "' | sudo tee /etc/dracut.conf.d/99-enable-resume.conf
sudo dracut -fv
Fedora 33 introduced some changes to the default partition scheme, specifically they started using ZRAM instead of a physical swap partition. Because of this, if you want to use hibernation in Fedora 33 and above, you will need to repartition your disk to include a swap partition (if you don’t already have one).